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The BRAF(V600E) causes widespread alterations in gene methylation in the genome of melanoma cells
Although BRAF(V600E) is well known to play an important role in the tumorigenesis of melanoma, its molecular mechanism, particularly the epigenetic aspect, has been incompletely understood. Here, we investigated the role of BRAF(V600E) signaling in altering gene methylation in the genome of melanoma...
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| Huvudupphovsmän: | , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Landes Bioscience
2012
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3293379/ https://ncbi.nlm.nih.gov/pubmed/22189819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.11.2.18707 |
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