Prolonged oral cannabinoid administration prevents neuroinflammation, lowers β-amyloid levels and improves cognitive performance in Tg APP 2576 mice

BACKGROUND: Alzheimer's disease (AD) brain shows an ongoing inflammatory condition and non-steroidal anti-inflammatories diminish the risk of suffering the neurologic disease. Cannabinoids are neuroprotective and anti-inflammatory agents with therapeutic potential. METHODS: We have studied the...

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Detalhes bibliográficos
Main Authors: Martín-Moreno, Ana María, Brera, Begoña, Spuch, Carlos, Carro, Eva, García-García, Luis, Delgado, Mercedes, Pozo, Miguel A, Innamorato, Nadia G, Cuadrado, Antonio, de Ceballos, María L
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3292807/
https://ncbi.nlm.nih.gov/pubmed/22248049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-8
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