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ACUTE INHIBITION OF CALCINEURIN RESTORES ASSOCIATIVE LEARNING AND MEMORY IN Tg2576 APP TRANSGENIC MICE
Misfolded amyloid beta peptide (Aβ) is a pathological hallmark of Alzheimer’s disease (AD), a neurodegenerative illness characterized by cognitive deficits and neuronal loss. Transgenic mouse models of Aβ over-production indicate that Aβ-induced cognitive deficits occur in the absence of overt neuro...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2031869/ https://ncbi.nlm.nih.gov/pubmed/17521929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nlm.2007.03.010 |
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