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AMYLOID BETA OLIGOMERS IMPAIR FEAR CONDITIONED MEMORY IN A CALCINEURIN-DEPENDENT FASHION IN MICE
Soluble oligomeric aggregates of the amyloid beta (Aβ) peptide are believed to be the most neurotoxic Aβ species affecting the brain in Alzheimer Disease (AD), a terminal neurodegenerative disorder involving severe cognitive decline underlined by initial synaptic dysfunction and later extensive neur...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2919647/ https://ncbi.nlm.nih.gov/pubmed/20544830 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.22445 |
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