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Stereoselective Synthesis of Both Tetrahydropyran Rings of the Antitumor Macrolide, (−)-Lasonolide A

Stereoselective syntheses of both functionalized tetrahydropyran subunits of (−)-lasonolide A are described. These tetrahydropyran rings were constructed using catalytic asymmetric hetero Diels-Alder reactions as the key steps. The C22 quaternary stereocenter present in the upper tetrahydropyran rin...

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Main Authors: Ghosh, Arun K., Ren, Guo-Bao
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3292631/
https://ncbi.nlm.nih.gov/pubmed/22324913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo202631e
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