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Stereoselective Synthesis of Both Tetrahydropyran Rings of the Antitumor Macrolide, (−)-Lasonolide A
Stereoselective syntheses of both functionalized tetrahydropyran subunits of (−)-lasonolide A are described. These tetrahydropyran rings were constructed using catalytic asymmetric hetero Diels-Alder reactions as the key steps. The C22 quaternary stereocenter present in the upper tetrahydropyran rin...
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Main Authors: | , |
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格式: | Artigo |
語言: | Inglês |
出版: |
2012
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3292631/ https://ncbi.nlm.nih.gov/pubmed/22324913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo202631e |
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