The Responsiveness of TrkB to BDNF and Antidepressant Drugs Is Differentially Regulated during Mouse Development

BACKGROUND: Previous studies suggest that the responsiveness of TrkB receptor to BDNF is developmentally regulated in rats. Antidepressant drugs (AD) have been shown to increase TrkB signalling in the adult rodent brain, and recent findings implicate a BDNF-independent mechanism behind this phenomen...

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Autori principali: Di Lieto, Antonio, Rantamäki, Tomi, Vesa, Liisa, Yanpallewar, Sudhirkumar, Antila, Hanna, Lindholm, Jesse, Rios, Maribel, Tessarollo, Lino, Castrén, Eero
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3292581/
https://ncbi.nlm.nih.gov/pubmed/22396798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032869
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