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Mice with altered BDNF signaling as models for mood disorders and antidepressant effects

Brain-derived neurotrophic factor (BDNF) and its receptor tyrosine kinase TrkB support neuronal survival during development and promote connectivity and plasticity in the adult brain. Decreased BDNF signaling is associated with the pathophysiology of depression and the mechanisms underlying the acti...

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Bibliografiske detaljer
Main Authors: Lindholm, Jesse S. O., Castrén, Eero
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012208/
https://ncbi.nlm.nih.gov/pubmed/24817844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnbeh.2014.00143
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