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RNA Interference Inhibition of Mus81 Reduces Mitotic Recombination in Human Cells
Mus81 is a highly conserved endonuclease with homology to the XPF subunit of the XPF-ERCC1 complex. In yeast Mus81 associates with a second subunit, Eme1 or Mms4, which is essential for endonuclease activity in vitro and for in vivo function. Human Mus81 binds to a homolog of fission yeast Eme1 in v...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The American Society for Cell Biology
2004
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC329235/ https://ncbi.nlm.nih.gov/pubmed/14617801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-08-0580 |
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