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RNA Interference Inhibition of Mus81 Reduces Mitotic Recombination in Human Cells

Mus81 is a highly conserved endonuclease with homology to the XPF subunit of the XPF-ERCC1 complex. In yeast Mus81 associates with a second subunit, Eme1 or Mms4, which is essential for endonuclease activity in vitro and for in vivo function. Human Mus81 binds to a homolog of fission yeast Eme1 in v...

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Detalhes bibliográficos
Main Authors: Blais, Veronique, Gao, Hui, Elwell, Cherilyn A., Boddy, Michael N., Gaillard, Pierre-Henri L., Russell, Paul, McGowan, Clare H.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC329235/
https://ncbi.nlm.nih.gov/pubmed/14617801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-08-0580
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