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Revisiting inward rectification: K ions permeate through Kir2.1 channels during high-affinity block by spermidine

Outward currents through Kir2.1 channels play crucial roles in controlling the electrical properties of excitable cells, and such currents are subjected to voltage-dependent block by intracellular Mg(2+) and polyamines that bind to both high- and low-affinity sites on the channels. Under physiologic...

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Detalhes bibliográficos
Main Authors: Liu, Tai-An, Chang, Hsueh-Kai, Shieh, Ru-Chi
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3290795/
https://ncbi.nlm.nih.gov/pubmed/22371365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201110736
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