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A difference in inward rectification and polyamine block and permeation between the Kir2.1 and Kir3.1/Kir3.4 K(+) channels
Inward rectification is caused by voltage-dependent block of the channel pore by intracellular Mg(2)(+) and polyamines such as spermine. In the present study, we compared inward rectification in the Kir3.1/Kir3.4 channel, which underlies the cardiac current I(K,ACh), and the Kir2.1 channel, which un...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1464189/ https://ncbi.nlm.nih.gov/pubmed/16109731 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.085746 |
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