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Base of Pore Loop Is Important for Rectification, Activation, Permeation, and Block of Kir3.1/Kir3.4
The Kir3.1/Kir3.4 channel is an inward rectifier, agonist-activated K(+) channel. The location of the binding site within the channel pore that coordinates polyamines (and is thus responsible for inward rectification) and the location of the gate that opens the channel in response to agonist activat...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Biophysical Society
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1459495/ https://ncbi.nlm.nih.gov/pubmed/16513790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.073569 |
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