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Determinants within the Turret and Pore-Loop Domains of KCNQ3 K(+) Channels Governing Functional Activity

KCNQ1–5 (Kv7.1–7.5) subunits assemble to form a variety of functional K(+) channels in the nervous system, heart, and epithelia. KCNQ1 and KCNQ4 homomers and KCNQ2/3 heteromers yield large currents, whereas KCNQ2 and KCNQ3 homomers yield small currents. Since the unitary conductance of KCNQ3 is five...

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Detalhes bibliográficos
Main Authors: Zaika, Oleg, Hernandez, Ciria C., Bal, Manjot, Tolstykh, Gleb P., Shapiro, Mark S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586577/
https://ncbi.nlm.nih.gov/pubmed/18790849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.137604
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