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Determinants within the Turret and Pore-Loop Domains of KCNQ3 K(+) Channels Governing Functional Activity
KCNQ1–5 (Kv7.1–7.5) subunits assemble to form a variety of functional K(+) channels in the nervous system, heart, and epithelia. KCNQ1 and KCNQ4 homomers and KCNQ2/3 heteromers yield large currents, whereas KCNQ2 and KCNQ3 homomers yield small currents. Since the unitary conductance of KCNQ3 is five...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2586577/ https://ncbi.nlm.nih.gov/pubmed/18790849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.137604 |
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