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Homomeric and Heteromeric Assembly of KCNQ (Kv7) K(+) Channels Assayed by Total Internal Reflection Fluorescence/Fluorescence Resonance Energy Transfer and Patch Clamp Analysis

M-type K(+) channels, consisting of KCNQ1–5 (Kv7.1–7.5) subunits, form a variety of homomeric and heteromeric channels. Whereas all the subunits can assemble into homomeric channels, the ability of the subunits to assemble into heteromultimers is highly variable. KCNQ3 is widely thought to co-assemb...

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Bibliographische Detailangaben
Hauptverfasser: Bal, Manjot, Zhang, Jie, Zaika, Oleg, Hernandez, Ciria C., Shapiro, Mark S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2576536/
https://ncbi.nlm.nih.gov/pubmed/18786918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805216200
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