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Diclofenac Distinguishes among Homomeric and Heteromeric Potassium Channels Composed of KCNQ4 and KCNQ5 Subunits

KCNQ4 and KCNQ5 potassium channel subunits are expressed in vascular smooth muscle cells, although it remains uncertain how these subunits assemble to form functional channels. Using patch-clamp techniques, we compared the electrophysiological characteristics and effects of diclofenac, a known KCNQ...

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Main Authors: Brueggemann, Lioubov I., Mackie, Alexander R., Martin, Jody L., Cribbs, Leanne L., Byron, Kenneth L.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014280/
https://ncbi.nlm.nih.gov/pubmed/20876743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.110.067496
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