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Cyclin E1 is a common target of BMI1 and MYCN and a prognostic marker for neuroblastoma progression
The Polycomb transcription repressor BMI1 is highly expressed in human neuroblastomas and is required for the clonogenic self-renewal and tumorigenicity of human neuroblastoma cell lines. The molecular basis of BMI1 action in neuroblastoma cells is not well understood. Here we report that BMI1 has a...
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| Главные авторы: | , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3290747/ https://ncbi.nlm.nih.gov/pubmed/22120721 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.536 |
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