Cyclin E1 is a common target of BMI1 and MYCN and a prognostic marker for neuroblastoma progression

The Polycomb transcription repressor BMI1 is highly expressed in human neuroblastomas and is required for the clonogenic self-renewal and tumorigenicity of human neuroblastoma cell lines. The molecular basis of BMI1 action in neuroblastoma cells is not well understood. Here we report that BMI1 has a...

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Detalhes bibliográficos
Main Authors: Mao, Ling, Ding, Jane, Perdue, Aja, Yang, Liqun, Zha, Yunhong, Ren, Mingqiang, Huang, Shuang, Cui, Hongjuan, Ding, Han-Fei
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3290747/
https://ncbi.nlm.nih.gov/pubmed/22120721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.536
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