MYCN Promotes the Expansion of Phox2B-Positive Neuronal Progenitors to Drive Neuroblastoma Development

Amplification of the oncogene MYCN is a tumorigenic event in the development of a subset of neuroblastomas that commonly consist of undifferentiated or poorly differentiated neuroblasts with unfavorable clinical outcome. The cellular origin of these neuroblasts is unknown. Additionally, the cellular...

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Detalhes bibliográficos
Main Authors: Alam, Goleeta, Cui, Hongjuan, Shi, Huilin, Yang, Liqun, Ding, Jane, Mao, Ling, Maltese, William A., Ding, Han-Fei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2009
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2716980/
https://ncbi.nlm.nih.gov/pubmed/19608868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.090019
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