Bmi-1 Is Essential for the Tumorigenicity of Neuroblastoma Cells

Activation of oncogenes underlies the pathogenesis of most human cancers. In neuroblastoma, amplification of the oncogene MYCN occurs in ∼22% of cases and is associated with advanced stages of the disease and poor prognosis. Identification of other oncogenes that are consistently mutated or overexpr...

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Autori principali: Cui, Hongjuan, Hu, Bo, Li, Tai, Ma, Jun, Alam, Goleeta, Gunning, William T., Ding, Han-Fei
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2007
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Regular Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1829469/
https://ncbi.nlm.nih.gov/pubmed/17392175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.060754
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