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Bmi-1 Is Essential for the Tumorigenicity of Neuroblastoma Cells
Activation of oncogenes underlies the pathogenesis of most human cancers. In neuroblastoma, amplification of the oncogene MYCN occurs in ∼22% of cases and is associated with advanced stages of the disease and poor prognosis. Identification of other oncogenes that are consistently mutated or overexpr...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Investigative Pathology
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1829469/ https://ncbi.nlm.nih.gov/pubmed/17392175 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.060754 |
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