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Enhanced Notch Activation Is Advantageous but Not Essential for T Cell Lymphomagenesis in Id1 Transgenic Mice

T cell lymphoblastic leukemia (T-ALL) is known to be associated with chromosomal abnormalities that lead to aberrant expression of a number of transcription factors such as TAL1, which dimerizes with basic helix-loop-helix (bHLH) E proteins and inhibits their function. Activated Notch receptors also...

詳細記述

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書誌詳細
主要な著者: Wang, Hong-Cheng, Peng, Vincent, Zhao, Ying, Sun, Xiao-Hong
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3290631/
https://ncbi.nlm.nih.gov/pubmed/22393458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032944
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