Hes1 Potentiates T Cell Lymphomagenesis by Up-Regulating a Subset of Notch Target Genes

BACKGROUND: Hairy/Enhancer of Split (Hes) proteins are targets of the Notch signaling pathway and make up a class of basic helix-loop-helix (bHLH) proteins that function to repress transcription. Data from Hes1 deficient mice suggested that Hes1, like Notch1, is necessary for the progression of earl...

Full description

Saved in:
Bibliographic Details
Main Authors: Dudley, Darryll D., Wang, Hong-Cheng, Sun, Xiao-Hong
Format: Artigo
Language:Inglês
Published: Public Library of Science 2009
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722736/
https://ncbi.nlm.nih.gov/pubmed/19688092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006678
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items