A simple procedure for the preparation of protected 2'-O-methyl or 2'-O-ethyl ribonucleoside-3'-O-phosphoramidites.

Protected 2'-O-methyl and 2'-O-ethyl ribonucleoside-3'-O-phosphoramidites were prepared via alkylation of the ribonucleosides at an early stage in the synthesis. Utilizing a strategy of minimal protection, the alkylation was performed with unprotected cytidine and adenosine, or with O...

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Detalhes bibliográficos
Main Authors: Wagner, E, Oberhauser, B, Holzner, A, Brunar, H, Issakides, G, Schaffner, G, Cotten, M, Knollmüller, M, Noe, C R
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC329054/
https://ncbi.nlm.nih.gov/pubmed/1945882
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