2'-O-methyl, 2'-O-ethyl oligoribonucleotides and phosphorothioate oligodeoxyribonucleotides as inhibitors of the in vitro U7 snRNP-dependent mRNA processing event.

We describe the synthesis of 2'-O-methyl, 2'-O-ethyl oligoribonucleotides and phosphorothioate oligodeoxyribonucleotides and demonstrate their utility as inhibitors of the in vitro U7 snRNP-dependent mRNA processing event. These 2'-O-modified compounds were designed to possess the bin...

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Detalhes bibliográficos
Main Authors: Cotten, M, Oberhauser, B, Brunar, H, Holzner, A, Issakides, G, Noe, C R, Schaffner, G, Wagner, E, Birnstiel, M L
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC328180/
https://ncbi.nlm.nih.gov/pubmed/1710340
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