A simple procedure for the preparation of protected 2'-O-methyl or 2'-O-ethyl ribonucleoside-3'-O-phosphoramidites.

Protected 2'-O-methyl and 2'-O-ethyl ribonucleoside-3'-O-phosphoramidites were prepared via alkylation of the ribonucleosides at an early stage in the synthesis. Utilizing a strategy of minimal protection, the alkylation was performed with unprotected cytidine and adenosine, or with O...

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Pubblicato in:Nucleic Acids Res
Autori principali: Wagner, E, Oberhauser, B, Holzner, A, Brunar, H, Issakides, G, Schaffner, G, Cotten, M, Knollmüller, M, Noe, C R
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 1991
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329054/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1945882/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.21.5965
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