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Selective Inhibition of Hypoxia-Inducible Factor (HIF) Prolyl-Hydroxylase 1 Mediates Neuroprotection against Normoxic Oxidative Death via HIF- and CREB-Independent Pathways

Oxidative stress contributes to tissue injury in conditions ranging from cardiovascular disease to stroke, spinal cord injury, neurodegeneration, and perhaps even aging. Yet the efficacy of antioxidants in human disease has been mixed at best. We need a better understanding of the mechanisms by whic...

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Detaylı Bibliyografya
Asıl Yazarlar: Siddiq, Ambreena, Aminova, Leila R., Troy, Carol M., Suh, Kyungsun, Messer, Zachary, Semenza, Gregg L., Ratan, Rajiv R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Society for Neuroscience 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3290095/
https://ncbi.nlm.nih.gov/pubmed/19587290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1779-09.2009
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