O6-methylguanine inhibits the binding of transcription factors to DNA.
To study the effect of methylation of O6-guanine on the binding of cellular factors to different DNA sequences, modified oligonucleotides were constructed, in which O6-Methylguanine (O6-MeG) replaced some guanines. The DNA sequences utilized were: the region of the c-fos promoter containing the bind...
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| Publicado en: | Nucleic Acids Res |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
1991
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| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC328984/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1945851/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.20.5739 |
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