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Mechanism of cellular uptake of modified oligodeoxynucleotides containing methylphosphonate linkages.

The cellular uptake and intracellular distribution of methylphosphonate oligonucleotides (15 mers) has been examined using both 32P labeled and fluorescent labeled oligonucleotides. The cellular uptake process for methylphosphonate oligonucleotides is highly temperature dependent, with a major incre...

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Autors principals: Shoji, Y, Akhtar, S, Periasamy, A, Herman, B, Juliano, R L
Format: Artigo
Idioma:Inglês
Publicat: 1991
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC328955/
https://ncbi.nlm.nih.gov/pubmed/1658734
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