Cellular uptake and biological effects of antisense oligodeoxynucleotide analogs targeted to herpes simplex virus.

In this study, we synthesized antisense oligodeoxynucleotides (ODNs) with phosphodiester, phosphorothioate (S-ODNs), or methylphosphonate linkages complementary to the splicing acceptor site of immediate-early pre-mRNA 5 of herpes simplex virus type 1 (HSV-1). The antiviral activity of each analog o...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Shoji, Y, Shimada, J, Mizushima, Y, Iwasawa, A, Nakamura, Y, Inouye, K, Azuma, T, Sakurai, M, Nishimura, T
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163393/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8807060/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.7.1670
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