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Mechanism of cellular uptake of modified oligodeoxynucleotides containing methylphosphonate linkages.

The cellular uptake and intracellular distribution of methylphosphonate oligonucleotides (15 mers) has been examined using both 32P labeled and fluorescent labeled oligonucleotides. The cellular uptake process for methylphosphonate oligonucleotides is highly temperature dependent, with a major incre...

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Autores principales: Shoji, Y, Akhtar, S, Periasamy, A, Herman, B, Juliano, R L
Formato: Artigo
Lenguaje:Inglês
Publicado: 1991
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC328955/
https://ncbi.nlm.nih.gov/pubmed/1658734
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