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Hypoxia-inducible factor-1α regulates KCNMB1 expression in human pulmonary artery smooth muscle cells

Previously, we observed that hypoxia increases the expression of the β1-subunit (KCNMB1) of the calcium-sensitive potassium channel (BK(Ca)). Herein, we elucidate the mechanism whereby hypoxia increases KCNMB1 expression in human pulmonary artery smooth muscle cells (hPASMC). In response to hypoxia,...

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Autors principals: Ahn, Yong-Tae, Kim, Yu-Mee, Adams, Eloa, Lyu, Shu-Chen, Alvira, Cristina M., Cornfield, David N.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289270/
https://ncbi.nlm.nih.gov/pubmed/22114151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00302.2011
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