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Rho kinase modulates postnatal adaptation of the pulmonary circulation through separate effects on pulmonary artery endothelial and smooth muscle cells

At birth, pulmonary vasodilation occurs concomitant with the onset of air-breathing life. Whether and how Rho kinase (ROCK) modulates the perinatal pulmonary vascular tone remains incompletely understood. To more fully characterize the separate and interactive effects of ROCK signaling, we hypothesi...

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Autori principali: Alvira, Cristina M., Sukovich, David J., Lyu, Shu-Chen, Cornfield, David N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3006275/
https://ncbi.nlm.nih.gov/pubmed/20709731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00199.2010
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