Pulmonary artery smooth muscle cell HIF-1α regulates endothelin expression via microRNA-543

Pulmonary artery smooth muscle cells (PASMCs) express endothelin (ET-1), which modulates the pulmonary vascular response to hypoxia. Although cross-talk between hypoxia-inducible factor-1α (HIF-1α), an O(2)-sensitive transcription factor, and ET-1 is established, the cell-specific relationship betwe...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Wang, Ching-Chia, Ying, Lihua, Barnes, Elizabeth A., Adams, Eloa S., Kim, Francis Y., Engel, Karl W., Alvira, Cristina M., Cornfield, David N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6172620/
https://ncbi.nlm.nih.gov/pubmed/29745253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00475.2017
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