A transgenic model of central nervous system autoimmunity mediated by CD4(+) and CD8(+) T and B cells

Experimental autoimmune encephalomyelitis (EAE) is a widely used model of multiple sclerosis (MS). In NOD mice, EAE develops as a relapsing-remitting disease that transitions to a chronic progressive disease, making the NOD model the only mouse model that recapitulates the full clinical disease cour...

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Main Authors: Anderson, Ana C., Chandwaskar, Rucha, Lee, David H., Sullivan, Jenna M., Solomon, Adam, Rodriguez-Manzanet, Roselynn, Greve, Bernhard, Sobel, Raymond A., Kuchroo, Vijay K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288950/
https://ncbi.nlm.nih.gov/pubmed/22279107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102186
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