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Myelin Oligodendrocyte Glycoprotein–specific T Cell Receptor Transgenic Mice Develop Spontaneous Autoimmune Optic Neuritis

Multiple sclerosis (MS) is considered to be an autoimmune disease of the central nervous system (CNS) that in many patients first presents clinically as optic neuritis. The relationship of optic neuritis to MS is not well understood. We have generated novel T cell receptor (TCR) transgenic mice spec...

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Detalhes bibliográficos
Main Authors: Bettelli, Estelle, Pagany, Maria, Weiner, Howard L., Linington, Christopher, Sobel, Raymond A., Kuchroo, Vijay K.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193967/
https://ncbi.nlm.nih.gov/pubmed/12732654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20021603
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