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Total Synthesis of the α-Subunit of the Human Glycoprotein Hormones (hGPH): Toward Fully Synthetic Homogeneous Human Follicle-Stimulating Hormone (hFSH)
Described herein is the first total chemical synthesis of the unique α-subunit of the human glycoprotein hormone (α-hGPH). Unlike the biologically–derived glycoprotein hormones, which are isolated as highly complex mixtures of glycoforms, α-hGPH obtained by chemical synthesis contains discrete homog...
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| Päätekijät: | , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2012
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3288947/ https://ncbi.nlm.nih.gov/pubmed/22280541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja2111459 |
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