Delivery of Bordetella pertussis adenylate cyclase toxin to target cells via outer membrane vesicles

B.pertussis adenylate cyclase toxin (ACT) intoxicates cells by producing intracellular cAMP. B.pertussis outer membrane vesicles (OMV) contain ACT on their surface (OMV-ACT), but the properties of OMV-ACT were previously unknown. We found that B.pertussis in the lung from a fatal pertussis case cont...

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Autori principali: Donato, Gina M., Goldsmith, Cynthia S., Paddock, Christopher D., Eby, Joshua C., Gray, Mary C., Hewlett, Erik L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288663/
https://ncbi.nlm.nih.gov/pubmed/22289177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2012.01.032
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