Quantification of the Adenylate Cyclase Toxin of Bordetella pertussis In Vitro and during Respiratory Infection

Whooping cough results from infection of the respiratory tract with Bordetella pertussis, and the secreted adenylate cyclase toxin (ACT) is essential for the bacterium to establish infection. Despite extensive study of the mechanism of ACT cytotoxicity and its effects over a range of concentrations...

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Detalhes bibliográficos
Main Authors: Eby, Joshua C., Gray, Mary C., Warfel, Jason M., Paddock, Christopher D., Jones, Tara F., Day, Shandra R., Bowden, James, Poulter, Melinda D., Donato, Gina M., Merkel, Tod J., Hewlett, Erik L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Bacterial Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648026/
https://ncbi.nlm.nih.gov/pubmed/23429530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00110-13
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