Quantification of the Adenylate Cyclase Toxin of Bordetella pertussis In Vitro and during Respiratory Infection

Whooping cough results from infection of the respiratory tract with Bordetella pertussis, and the secreted adenylate cyclase toxin (ACT) is essential for the bacterium to establish infection. Despite extensive study of the mechanism of ACT cytotoxicity and its effects over a range of concentrations...

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Autores principales: Eby, Joshua C., Gray, Mary C., Warfel, Jason M., Paddock, Christopher D., Jones, Tara F., Day, Shandra R., Bowden, James, Poulter, Melinda D., Donato, Gina M., Merkel, Tod J., Hewlett, Erik L.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2013
Materias:
Bacterial Infections
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648026/
https://ncbi.nlm.nih.gov/pubmed/23429530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00110-13
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