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Delivery of Bordetella pertussis adenylate cyclase toxin to target cells via outer membrane vesicles

B.pertussis adenylate cyclase toxin (ACT) intoxicates cells by producing intracellular cAMP. B.pertussis outer membrane vesicles (OMV) contain ACT on their surface (OMV-ACT), but the properties of OMV-ACT were previously unknown. We found that B.pertussis in the lung from a fatal pertussis case cont...

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Autors principals: Donato, Gina M., Goldsmith, Cynthia S., Paddock, Christopher D., Eby, Joshua C., Gray, Mary C., Hewlett, Erik L.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288663/
https://ncbi.nlm.nih.gov/pubmed/22289177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2012.01.032
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