Distinct kinetics of Gag-specific CD4+ and CD8+ T cell responses during acute HIV-1 infection

HIV infection is characterized by a gradual deterioration of immune function mainly in the CD4 compartment. To better understand the dynamics of HIV-specific T cells, we analyzed the kinetics and polyfunctional profiles of Gag-specific CD4+ and CD8+ T cell responses in 12 subtype C-infected individu...

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Detalhes bibliográficos
Main Authors: Riou, Catherine, Ganusov, Vitaly V., Campion, Suzanne, Mlotshwa, Mandla, Liu, Michael K.P., Whale, Victoria E., Goonetilleke, Nilu, Borrow, Persephone, Ferrari, Guido, Betts, Michael R., Haynes, Barton F., McMichael, Andrew J., Gray, Clive M
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288487/
https://ncbi.nlm.nih.gov/pubmed/22287716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102813
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