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Preferential control of induced regulatory T cell homeostasis via a Bim/Bcl-2 axis

Apoptosis has an essential role in controlling T cell homeostasis, especially during the contraction phase of an immune response. However, its contribution to the balance between effector and regulatory populations remains unclear. We found that Rag1(−/−) hosts repopulated with Bim(−/−) conventional...

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Detalhes bibliográficos
Main Authors: Wang, X, Szymczak-Workman, A L, Gravano, D M, Workman, C J, Green, D R, Vignali, D A A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288351/
https://ncbi.nlm.nih.gov/pubmed/22318539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2012.9
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