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Mechanisms for quality control of misfolded transmembrane proteins

To prevent the accumulation of misfolded and aggregated proteins, the cell has developed a complex network of cellular quality control (QC) systems to recognize misfolded proteins and facilitate their refolding or degradation. The cell faces numerous obstacles when performing quality control on tran...

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Bibliografiske detaljer
Main Authors: Houck, Scott A., Cyr, Douglas M.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288195/
https://ncbi.nlm.nih.gov/pubmed/22100602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2011.11.007
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