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A Co-Translational Ubiquitination Pathway For Quality Control of Misfolded Proteins
Previous studies have indicated that 6–30% of all newly synthesized proteins are rapidly degraded by the ubiquitin-proteasome system, however the relationship of ubiquitination to translation for these proteins has been unclear. We report that co-translational ubiquitination (CTU) is a robust proces...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3654026/ https://ncbi.nlm.nih.gov/pubmed/23583076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.03.009 |
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