Direct evidence of nuclear Argonaute distribution during transcriptional silencing links the actin cytoskeleton to nuclear RNAi machinery in human cells

Mammalian RNAi machinery facilitating transcriptional gene silencing (TGS) is the RNA-induced transcriptional gene silencing-like (RITS-like) complex, comprising of Argonaute (Ago) and small interfering RNA (siRNA) components. We have previously demonstrated promoter-targeted siRNA induce TGS in hum...

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Autori principali: Ahlenstiel, Chantelle L., Lim, Heidi G. W., Cooper, David A., Ishida, Takaomi, Kelleher, Anthony D., Suzuki, Kazuo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2012
Soggetti:
Gene Regulation, Chromatin and Epigenetics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287199/
https://ncbi.nlm.nih.gov/pubmed/22064859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr891
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