Direct evidence of nuclear Argonaute distribution during transcriptional silencing links the actin cytoskeleton to nuclear RNAi machinery in human cells

Mammalian RNAi machinery facilitating transcriptional gene silencing (TGS) is the RNA-induced transcriptional gene silencing-like (RITS-like) complex, comprising of Argonaute (Ago) and small interfering RNA (siRNA) components. We have previously demonstrated promoter-targeted siRNA induce TGS in hum...

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Bibliografiske detaljer
Main Authors: Ahlenstiel, Chantelle L., Lim, Heidi G. W., Cooper, David A., Ishida, Takaomi, Kelleher, Anthony D., Suzuki, Kazuo
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2012
Fag:
Gene Regulation, Chromatin and Epigenetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287199/
https://ncbi.nlm.nih.gov/pubmed/22064859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr891
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