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Closed Chromatin Architecture Is Induced by an RNA Duplex Targeting the HIV-1 Promoter Region
In some mammalian systems small interfering RNAs (siRNA) targeting homologous sequences in promoter regions of genes induce transcriptional gene silencing (TGS). We have previously reported the induction of TGS by an siRNA (prom-A siRNA) targeting the tandem NF-κB-binding motifs within the human imm...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2516975/ https://ncbi.nlm.nih.gov/pubmed/18519571 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M709651200 |
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