Integrated molecular profiles of invasive breast tumors and ductal carcinoma in situ (DCIS) reveal differential vascular and interleukin signaling

We use an integrated approach to understand breast cancer heterogeneity by modeling mRNA, copy number alterations, microRNAs, and methylation in a pathway context utilizing the pathway recognition algorithm using data integration on genomic models (PARADIGM). We demonstrate that combining mRNA expre...

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Main Authors: Kristensen, Vessela N., Vaske, Charles J., Ursini-Siegel, Josie, Van Loo, Peter, Nordgard, Silje H., Sachidanandam, Ravi, Sørlie, Therese, Wärnberg, Fredrik, Haakensen, Vilde D., Helland, Åslaug, Naume, Bjørn, Perou, Charles M., Haussler, David, Troyanskaya, Olga G., Børresen-Dale, Anne-Lise
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2012
Teme:
Breast Cancer Special Feature
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286992/
https://ncbi.nlm.nih.gov/pubmed/21908711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1108781108
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