Integrated molecular profiles of invasive breast tumors and ductal carcinoma in situ (DCIS) reveal differential vascular and interleukin signaling

We use an integrated approach to understand breast cancer heterogeneity by modeling mRNA, copy number alterations, microRNAs, and methylation in a pathway context utilizing the pathway recognition algorithm using data integration on genomic models (PARADIGM). We demonstrate that combining mRNA expre...

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Detalhes bibliográficos
Main Authors: Kristensen, Vessela N., Vaske, Charles J., Ursini-Siegel, Josie, Van Loo, Peter, Nordgard, Silje H., Sachidanandam, Ravi, Sørlie, Therese, Wärnberg, Fredrik, Haakensen, Vilde D., Helland, Åslaug, Naume, Bjørn, Perou, Charles M., Haussler, David, Troyanskaya, Olga G., Børresen-Dale, Anne-Lise
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Breast Cancer Special Feature
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286992/
https://ncbi.nlm.nih.gov/pubmed/21908711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1108781108
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