Genome-wide DNA methylation profiles in progression to in situ and invasive carcinoma of the breast with impact on gene transcription and prognosis

BACKGROUND: Ductal carcinoma in situ (DCIS) of the breast is a precursor of invasive breast carcinoma. DNA methylation alterations are thought to be an early event in progression of cancer, and may prove valuable as a tool in clinical decision making and for understanding neoplastic development. RES...

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Main Authors: Fleischer, Thomas, Frigessi, Arnoldo, Johnson, Kevin C, Edvardsen, Hege, Touleimat, Nizar, Klajic, Jovana, Riis, Margit LH, Haakensen, Vilde D, Wärnberg, Fredrik, Naume, Bjørn, Helland, Åslaug, Børresen-Dale, Anne-Lise, Tost, Jörg, Christensen, Brock C, Kristensen, Vessela N
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4165906/
https://ncbi.nlm.nih.gov/pubmed/25146004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-014-0435-x
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