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Mechanistic insight into Myc stabilization in breast cancer involving aberrant Axin1 expression

High expression of the oncoprotein Myc has been linked to poor outcome in human tumors. Although MYC gene amplification and translocations have been observed, this can explain Myc overexpression in only a subset of human tumors. Myc expression is in part controlled by its protein stability, which ca...

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Autori principali: Zhang, Xiaoli, Farrell, Amy S., Daniel, Colin J., Arnold, Hugh, Scanlan, Charles, Laraway, Bryan J., Janghorban, Mahnaz, Lum, Lawrence, Chen, Dexi, Troxell, Megan, Sears, Rosalie
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286933/
https://ncbi.nlm.nih.gov/pubmed/21808024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1100764108
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