Pin1 Regulates the Dynamics of c-Myc DNA Binding To Facilitate Target Gene Regulation and Oncogenesis

The Myc oncoprotein is considered a master regulator of gene transcription by virtue of its ability to modulate the expression of a large percentage of all genes. However, mechanisms that direct Myc's recruitment to DNA and target gene selection to elicit specific cellular functions have not be...

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Bibliographic Details
Main Authors: Farrell, Amy S., Pelz, Carl, Wang, Xiaoyan, Daniel, Colin J., Wang, Zhiping, Su, Yulong, Janghorban, Mahnaz, Zhang, Xiaoli, Morgan, Charlie, Impey, Soren, Sears, Rosalie C.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719674/
https://ncbi.nlm.nih.gov/pubmed/23716601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01455-12
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