Post-translational modification localizes MYC to the nuclear pore basket to regulate a subset of target genes involved in cellular responses to environmental signals

The transcription factor MYC (also c-Myc) induces histone modification, chromatin remodeling, and the release of paused RNA polymerase to broadly regulate transcription. MYC is subject to a series of post-translational modifications that affect its stability and oncogenic activity, but how these con...

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Dettagli Bibliografici
Pubblicato in:Genes Dev
Autori principali: Su, Yulong, Pelz, Carl, Huang, Tao, Torkenczy, Kristof, Wang, Xiaoyan, Cherry, Allison, Daniel, Colin J., Liang, Juan, Nan, Xiaolin, Dai, Mu-Shui, Adey, Andrew, Impey, Soren, Sears, Rosalie C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2018
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217735/
https://ncbi.nlm.nih.gov/pubmed/30366908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.314377.118
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